New and Noteworthy | Flatiron Health

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Measurement error and bias in real-world oncology endpoints when constructing external control arms
Frontiers in Drug Safety and Regulation
An evaluation of patient activity definitions and informative censoring in analyses of real-world overall survival in electronic health records (EHR) in the United States
ISPE Annual Conference
Assessing the potential value of commercial mortality data combined with publicly available death data for pharmacoepidemiology research
ISPE Annual Conference
Assessment of the application of a 90-day-gap rule for mitigating frontline treatment sequence misclassification in electronic health records in the United States
ISPE Annual Conference
Assessing real-world data from electronic health records for health technology assessment: The SUITABILITY checklist: a good practices report of an ISPOR task force
Value in Health
Response- and progression-based endpoints in trial and observational cohorts of patients With NSCLC
JAMA Network Open
Performance assessment of a disease-agnostic treatment sequencing heuristic for deriving line of therapy in a real-world, rare, multi-tumor cohort across tumor mutational burden status
Poster presented at: ISPOR US 2024; May 5-8, 2024; Atlanta, GA
Applying the estimand and target trial frameworks to external control analyses using observational data: a case study in the solid tumor setting
Frontiers in Pharmacology
A framework for evaluating clinical artificial intelligence systems without ground-truth annotations
Nature Communications

Methodology