Overview
Non-small cell lung cancer (NSCLC) represents a significant portion of lung cancer cases globally, yet real-world data on treatment access and outcomes remain sparse. This study utilizes the Germany Flatiron Health Research Database to explore patient characteristics and treatment patterns among patients diagnosed with NSCLC between 1997 and 2024.
By leveraging electronic health records, the study provides a detailed view of patient demographics, clinical characteristics, and biomarker testing. The dataset highlights the frequencies of important biomarker testing; the available treatment modalities including surgery, radiation, and systemic therapies; and, how the treatment with systemic therapies has changed over time owing to the introduction of different immunotherapies and targeted therapies.
Why this matters
This research is crucial as it fills a significant gap in understanding real-world NSCLC management. The comprehensive dataset offers valuable insights into treatment patterns and biomarker testing, which are essential for tailoring personalized treatment strategies. By ensuring high data quality and completeness, the study supports evidence-based clinical decision-making and health policy development in Germany and beyond.