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Characterization of cancer clinical trials in the community setting


May 2024


Altomare I, Lu Y, Pal S, et al. Characterization of cancer clinical trials in the community setting. J Clin Oncol 42, 2024 (suppl 16; abstr e13506). 2024.


Expanding clinical trials to more community oncology sites is essential to achieving enrollment goals, enhancing the relevance of research findings, and fostering equal access to care. Yet, the types of trials that thrive in community settings may differ from those prevalent in academic centers. This research investigates the attributes of clinical trials carried out within a network of community oncology practices across the United States in recent years. By pinpointing trial characteristics well-suited to community settings, the study seeks to provide valuable guidance for sponsors and sites, assisting in the selection of studies most conducive to effective implementation in community environments.

Why this matters

This study highlights the critical role of community oncology practices in supporting a range of clinical trials, particularly those aimed at treating solid tumors. Community oncology practices support robust trial portfolios of Phase I-IV studies across a range of sponsors. However, the observation that many trials are limited to single sites within the community underscores the urgent need for enhanced collaboration and network utilization. By leveraging consortia and tech-enabled research networks, sponsors can promote broader community engagement and support expanded access to diverse trials, ultimately leading to improved patient care outcomes.

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