Overview
High-quality real-world data is crucial for understanding colorectal cancer in Japan, however, research has been limited by a lack of comprehensive, recent, and detailed data sources. This study examines treatment patterns in a cohort of patients with colorectal cancer in Japan, using the Japan Flatiron Health Research Database, which is derived from structured and unstructured data documented in electronic health records (EHR) during routine oncology care in Japan, and curated through technology-enabled abstraction with comprehensive quality verification processes.
By analyzing data from 1,534 patients, the study provides insight into patient clinical characteristics, biomarker testing and treatment patterns in a real-world Japanese cohort. This study revealed variability in clinical characteristics and treatment patterns among patients diagnosed with colorectal cancer in Japan, highlighting opportunities to optimize care.
Why this matters
This research fills critical gaps in existing colorectal cancer data by offering a detailed view of real-world care practices in Japan. The ability to harmonize this dataset with international counterparts from the US, UK, and Germany allows for a global perspective on colorectal cancer management. Such comprehensive data supports the development of personalized treatment strategies and highlights areas for improvement in clinical practice and paves the way for more effective interventions worldwide.